Brochures & Datasheets
04 Dec 2025
English
RESOURCE LIBRARY
Application Notes, Webinars & Papers
The evidence behind every Contichrom® process. Download the open-access PPQ paper, browse application notes by molecule, watch on-demand webinars, and access the peer-reviewed publications underpinning MCSGP, CaptureSMB®, and N-Rich® at GMP commercial scale.
Recent MCSGP Research Highlights
The first peer-reviewed PC/PPQ framework for MCSGP
The first peer-reviewed PC/PPQ framework for MCSGP. 95% IPC reduction, 73% PMI reduction, 96% gross-to-gross yield — validated at GMP commercial scale on Bachem Bivalirudin.
Eisenhuth, R. & Müller-Späth, T. — Processes, 2025 (Open-Access)
First peer-reviewed AIEX MCSGP for therapeutic siRNA
First peer-reviewed AIEX MCSGP for therapeutic siRNA. Yield improved from 80% to 93% on a sugar-conjugated siRNA sense strand — software-aided method development enabled fast batch-to-MCSGP transfer. Throughput increased 87%.
Weldon et al. Org. Process Res. Dev. 2025, (Open-Access)
Proof-of-concept MCSGP for AAV2 polishing
Proof-of-concept MCSGP for AAV2 polishing. Full capsid content increased from 30% to 68% (ddPCR) after six cycles — with +20.6% yield, +23% productivity, and 27% reduced buffer consumption vs batch AEX. AutoPeak® PAT validated against cryo-TEM and ddPCR.
Müller et al.
Biotechnol. Bioeng. (Open-Access)
Resource Library
Application notes, peer-reviewed papers, process guides, datasheets, and recorded webinars — searchable by application, technology, product, or service.
- All Media Types
- Application Notes
- Webinars & Videos
- Process Guides & Manuals
- Peer-Reviewed Publications
- Brochures & Datasheets
Process Guides & Manuals
04 Dec 2025
English
Brochures & Datasheets
04 Dec 2025
English
Contichrom CUBE Brochure
Batch Chromatography
Continuous Capture (CaptureSMB®)
Continuous Enrichment (N-Rich®)
Continuous Polishing (MCSGP)
Dynamic Process Control (AutoPeak® & AutomAb®)
Multi-Dimensional Chromatography (2D/3D)
System Rentals
Demos & Introductions
Contichrom® CUBE
Antibody-drug Conjugates
Impurity Isolation
mAbs & Antibody Variants
Small Molecules & Nutraceuticals
Oligonucleotides
Recombinant Proteins
Peptides
Viral Vectors (AAV)
Educational Articles
Fundamentals of Preparative Chromatography
25 Nov 2025
Part I – What Is Chromatography? The Universal Primer for New Scientists
A practical primer on chromatography: what it is, how it works, and why it matters. Learn about key separation mechanisms including reversed-phase, ion exchange, size exclusion and affinity chromatography, plus how to read chromatograms and the difference between analytical and preparative methods.
YMC ChromaCon Chromatography Newsletter.
Subscribe for New Resources Unsubscribe anytime.