APPLICATIONS

Purification Applications

Continuous chromatography for every major molecule class. From therapeutic peptides and oligonucleotides to monoclonal antibodies, ADCs, viral vectors, and beyond. Eight molecule classes, one platform.

One Platform for Every Molecule

The Contichrom® platform supports the purification of the full spectrum of biopharmaceutical molecules — using the same hardware for batch, 2D/3D integrated, and continuous chromatography processes. Whether your challenge is maximizing yield on a complex peptide, increasing resin utilization during mAb capture, or isolating low-abundance impurities for regulatory characterization, our technologies are proven across molecule classes from laboratory development through GMP manufacturing.

Select an application below to see how Contichrom technologies address the specific purification challenges for your molecule.

Choose Your Application

From peptides to viral vectors — multiple molecule classes, one platform.

Peptides
Peptides

MCSGP with AutoPeak® achieves scalable, cost-effective purification for complex synthetic peptides, maximizing recovery by automatically recycling low purity side-cuts.

Oligonucleotides
Oligonucleotides

MCSGP with AutoPeak® breaks the yield-purity tradeoff delivering higher oligonucleotide yields without sacrificing purity.

mAbs & Antibody Variants
mAbs & Antibody Variants

CaptureSMB® with AutomAb® for mAbs & antibody variants: maximize productivity and resin utilization, while slashing buffer consumption.

Antibody-drug Conjugates
Antibody-drug Conjugates

MCSGP with AutoPeak® is ideally suited for DAR control, achieving precise drug-antibody ratios with higher yield than batch chromatography.

Recombinant Proteins
Recombinant Proteins

From capture through polishing, Contichrom® integrates multiple chromatography steps into automated 2D/3D workflows — reducing hands-on time and intermediate handling.

Viral Vectors (AAV)
Viral Vectors (AAV)

Continuous chromatography improves full/empty capsid separation and recovery, supporting scalable AAV manufacturing.

Small Molecules & Nutraceuticals
Small Molecules & Nutraceuticals

High-pressure continuous chromatography on the Contichrom® platform enables efficient purification of natural compounds and small molecules at preparative scale.

Impurity Isolation
Impurity Isolation

N-Rich automates on-column enrichment of low-abundance impurities, replacing weeks of repetitive HPLC runs with a single automated process.

Frequently Asked Questions