{"id":805,"date":"2025-11-17T11:40:00","date_gmt":"2025-11-17T11:40:00","guid":{"rendered":"https:\/\/chromocan.test\/?post_type=technology&p=805"},"modified":"2026-05-11T11:42:07","modified_gmt":"2026-05-11T09:42:07","slug":"batch-chromatography","status":"publish","type":"technology","link":"https:\/\/www.chromacon.com\/en\/technologies\/batch-chromatography\/","title":{"rendered":"Batch Chromatography"},"content":{"rendered":"
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\n BATCH CHROMATOGRAPHY <\/p>\n \n

\n Contichrom\u00ae CUBE. <\/strong>Built for Batch and Continuous Chromatography\n <\/h1>\n \n
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Ready to use out of the box. Four pumps and twin-column architecture in a single bench-top system. Run high-pressure batch chromatography today \u2014 and switch to MCSGP, CaptureSMB\u00ae, or N-Rich\u00ae on the same hardware whenever you’re ready. No second system. No method redevelopment.<\/p>\n <\/div>\n <\/div>\n\n

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\n Book a CUBE Demo<\/span><\/a><\/span> <\/div>\n
\n Download the CUBE Brochure<\/span><\/a><\/span> <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n
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\n Book a CUBE Demo<\/span><\/a><\/span> <\/div>\n
\n Download the CUBE Brochure<\/span><\/a><\/span> <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n
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\n Why Run Single-Column Batch on a Contichrom\u00ae CUBE? <\/h2>\n \n
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If the system is designed for twin-column continuous chromatography, why choose it for running in single-column batch mode? Because the same engineering that enables CaptureSMB\u00ae and MCSGP also makes the CUBE a genuinely better batch platform \u2014 before you ever consider continuous operation.<\/p>\n

– Out-of-the-box functionality.<\/strong> Four high-precision pumps, twin-column architecture, and 18 inlets are part of the base hardware. Most batch workflows run with no add-ons; advanced multi-step configurations have a clear upgrade path.<\/p>\n

– One platform, many modes.<\/strong> Single-column, alternating-batch, and 2D\/3D integrated batch all run on the same 100 bar hardware \u2014 supporting Protein A\/L\/G, IMAC, IEX, RP, Mixed-Mode, HIC, and SEC \u2014 isocratic or gradient.<\/p>\n

– Continuous-ready from day one.<\/strong> Every batch run becomes the starting point for MCSGP, N-Rich\u00ae, or CaptureSMB\u00ae \u2014 same hardware, same columns, same software. No second system. No method redevelopment.<\/p>\n

– Advanced method design. <\/strong>We make even the most challenging method designs easy to implement with ChromaCraft\u2122<\/strong>, our batch & 2D\/3D integrated batch method design module.<\/p>\n <\/div>\n \n <\/div>\n\n

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\n A twin-column, four-pump architecture \u2014 not a retrofit. <\/h2>\n \n
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The CUBE was engineered from day one as a twin-column platform \u2014 every component on the front face was designed to support continuous chromatography natively, not bolted onto a single-column system after the fact.<\/p>\n

Pump architecture<\/strong><\/p>\n