{"id":1866,"date":"2025-11-17T11:34:29","date_gmt":"2025-11-17T11:34:29","guid":{"rendered":"https:\/\/chromocan.test\/technology\/multi-column-chromatography\/"},"modified":"2026-05-12T14:10:25","modified_gmt":"2026-05-12T12:10:25","slug":"2d-3d-chromatography","status":"publish","type":"technology","link":"https:\/\/www.chromacon.com\/en\/technologies\/2d-3d-chromatography\/","title":{"rendered":"Multi-Dimensional Chromatography (2D\/3D)"},"content":{"rendered":"
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\n INTEGRATED CHROMATOGRAPHY <\/p>\n \n

\n Two or Three Steps. One Run. 2D\/3D<\/strong> Integrated Batch<\/strong>.\n <\/h1>\n \n
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Your batch method is already step one. ChromaCraft\u2122 adds the next \u2014 orchestrating multi-step purification on the Contichrom\u00ae CUBE in a single integrated run, with automated transfer, in-line dilution, and full method control across every dimension.<\/p>\n <\/div>\n <\/div>\n\n

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\n Request a Webinar<\/span><\/a><\/span> <\/div>\n
\n Download the CUBE Brochure<\/span><\/a><\/span> <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n
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\n Request a Webinar<\/span><\/a><\/span> <\/div>\n
\n Download the CUBE Brochure<\/span><\/a><\/span> <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n
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\n One System. Two or Three Purification Steps. <\/h2>\n \n
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The moment you run your first batch method on the Contichrom\u00ae CUBE, you have the foundation for a 2D purification process. The same hardware, columns, and ChromIQ\u00ae software that ran your Protein A capture can route the eluate directly onto a second column \u2014 IEX polishing, HIC, desalting \u2014 without breaking the run.<\/p>\n

The CUBE handles the handoff automatically:<\/p>\n